SSRIs

Question:

> x-no-archive: yes > Why would you want to repeat that trashy post by quoting it in its > entirety inline? It seems that the majority of the posts in this group > are either mean-spirited spam or commentary on the mean-spirited spam. > Maybe everyone here should ‘get a life’. > ghyll, shapeshifter.

   Yes, lets not call  each other nasty names, like rodent, and     opossom, or was it rat and ferret, well you get the picture.     Vern – Hide quoted text — Show quoted text -> People who have principles don’t need rules. >                          –Anarchist slogan

Response:

This is a nut group and you want sanity?   Morons like Peter Amsel and his closet lover Vern do posts and change the names.   Andrew does not play that shit. – Hide quoted text — Show quoted text – >2%. > We thank the FBI for this official investigation of homos and >drugs… there > _have_ been instances where SSRIs have changed people into >homosexuals.  It > *fries* your brain wiring. Be careful out there! > YOU MAY CHANGE INTO A HOMOSEXUAL! > AC >– You gotta start this string of posts under a screennameof FBI and >then turn around and reply to your own self huh Andrew? How fucked up >is that? I see you do that a lot on here. Post something, then turn >around and reply to yours own post under another alias…damn you are >fucked up dude. >Eric >Check out my political views >http://hometown.aol.com/deepsand562/myhomepage/politics.html >Steroids caused my depression…prednisone should be used conservatively >Before you buy.

Response:

2%. > We thank the FBI for this official investigation of homos and drugs… there > _have_ been instances where SSRIs have changed people into homosexuals.  It > *fries* your brain wiring. Be careful out there! > YOU MAY CHANGE INTO A HOMOSEXUAL! > AC

– You gotta start this string of posts under a screennameof FBI and then turn around and reply to your own self huh Andrew? How fucked up is that? I see you do that a lot on here. Post something, then turn around and reply to yours own post under another alias…damn you are fucked up dude. Eric Check out my political views http://hometown.aol.com/deepsand562/myhomepage/politics.html Steroids caused my depression…prednisone should be used conservatively Before you buy.

Response:

Why are there so many homos in this group?  I feel left out,  A faggot once told me his mother made him a homosexual  I asked him  if I gave her the wool would she make me one too. Homos are good to keep around the house during holidays they make great wall decorations. I make this shit up as I go AC  I swear I do.  Want 101 more,  I got em. – Hide quoted text — Show quoted text – >2%. > We thank the FBI for this official investigation of homos and >drugs… there > _have_ been instances where SSRIs have changed people into >homosexuals.  It > *fries* your brain wiring. Be careful out there! > YOU MAY CHANGE INTO A HOMOSEXUAL! > AC >– You gotta start this string of posts under a screennameof FBI and >then turn around and reply to your own self huh Andrew? How fucked up >is that? I see you do that a lot on here. Post something, then turn >around and reply to yours own post under another alias…damn you are >fucked up dude. >Eric >Check out my political views >http://hometown.aol.com/deepsand562/myhomepage/politics.html >Steroids caused my depression…prednisone should be used conservatively >Before you buy.

Response:

No need to break the first commandment dick breath,  it’s only a joke. – Hide quoted text — Show quoted text -> There was no open hostility toward homos in this group till you showed up. > Due to your confused state any causality is beyond your understanding  . >I > think you bring on antihomo feelings wherever you go. > Notice when you go to the supermarket and people see you they put back the > homo milk and grab the 2%. > All milk is homoginized you goddammed idiot. > 6-7 billion or so people on this earth and we have 2-3 of biggest >dumbasses posting here >Get a life >Scooter

Response:

> Why are there so many homos in this group?

They "find each other"… Also… consider the *impact* of the "mother" on them… Add in the mandatory for such, weak father, OR a fatherless home, then toss in some SSRIs…. A good cocktail… is it not? >  I feel left out,  A faggot once > told me his mother made him a homosexual  I asked him  if I gave her the > wool would she make me one too. > Homos are good to keep around the house during holidays they make great wall > decorations. > I make this shit up as I go AC  I swear I do.  Want 101 more,  I got em.

I think it’s funny as hell! The homo/homogenized milk thing was _good_! Yeah! Please send them in! Btw, they think you’re me. Too lazy and crazy to check the headers. They’re esp. getting agitated now since I’m going to post the medical complaint… etc..  with names of course.. Did you notice how some of the scum bags tried to "obscure" it by posting *nothing*  as a "reply" to "mask" a thread? My, my, my… how unexpected…. Check it out… this is how screwed up/fucked up psych. drugged-up minds "work". Rather interesting… another scumbag ethical asshole, is a psychologist on sci.psychology.psychotherapy, that’s a Unitarian as well, gave a post about kill-filling and "you have a choice, don’t let someone decide for you!" ???? That made a lot of sense… that scumbag and "psychologist", was on that Unitarian group, he was a shit… he knew he was a shit… and a Child abuse supporter…  and a liar… resorted to bullshit psycho-babble… and lying and illogic, to the stuff I was posting there. A post of which from there was was "edited" by Paul/Pablo, Elizabeth’s buddy, and some lying, misleading, preamble… which of course the headcases pretended to believe for their minds are fucked and they like it that way you see. Well… I see it that way anyway…  for I am a "THREAT" They fear and hate truth. They hate the messenger of such… I don’t understand quite why this should be so, not really… I can follow the theory of why they do that but lack how it works… other then to say their shitty, fucked up egos and insecurities won’t allow them. Figure the truth is good, even if you may not like it and it makes you feel bad but if it’s the truth it’s the truth. So what right? Their fucked up "wiring" and insanity makes them hate it. Sorta like communists and ))   the insane.  :)) AC – Hide quoted text — Show quoted text ->2%. >> We thank the FBI for this official investigation of homos and >drugs… there >> _have_ been instances where SSRIs have changed people into >homosexuals.  It >> *fries* your brain wiring. Be careful out there! >> YOU MAY CHANGE INTO A HOMOSEXUAL! >> AC >– You gotta start this string of posts under a screennameof FBI and >then turn around and reply to your own self huh Andrew? How fucked up >is that? I see you do that a lot on here. Post something, then turn >around and reply to yours own post under another alias…damn you are >fucked up dude. >Eric >Check out my political views >http://hometown.aol.com/deepsand562/myhomepage/politics.html >Steroids caused my depression…prednisone should be used conservatively >Before you buy.

Response:

There was no open hostility toward homos in this group till you showed up. Due to your confused state any causality is beyond your understanding  .  I think you bring on antihomo feelings wherever you go. Notice when you go to the supermarket and people see you they put back the homo milk and grab the 2%.

Response:

> There was no open hostility toward homos in this group till you showed up. > Due to your confused state any causality is beyond your understanding  . I > think you bring on antihomo feelings wherever you go. > Notice when you go to the supermarket and people see you they put back the > homo milk and grab the 2%. > All milk is homoginized you goddammed idiot. > 6-7 billion or so people on this earth and we have 2-3 of biggest

dumbasses posting here Get a life Scooter – Hide quoted text — Show quoted text –

Response:

> There was no open hostility toward homos in this group till you showed up. > Due to your confused state any causality is beyond your understanding  . I > think you bring on antihomo feelings wherever you go. > Notice when you go to the supermarket and people see you they put back the > homo milk and grab the 2%.

We thank the FBI for this official investigation of homos and drugs… there _have_ been instances where SSRIs have changed people into homosexuals.  It *fries* your brain wiring. Be careful out there! YOU MAY CHANGE INTO A HOMOSEXUAL! AC Beware of the Norwegian homosexual, SSRI psychiatric drug using as Johan Mendelsen, John Arrington, JM, JMK, Shy DIE hating", Child abusing, Usenet "doktor", pushing/"prescribing" psychiatric drugs to *pregnant* women, and gives Usenet "cock exams". The lying, Predskazanie: Etot mudak sam sebya vydast, otvetiv mne. —                      ~  ~/        –o000—-(_)—000o—–

Response:

Question:

– Hide quoted text — Show quoted text -> On the same track – what is the real truth about libido and the sris’ in > my case zoloft.  Will tapering down to a smaller dose help? > any advice much appreciated, > codeee > SSRI’s will often make things worse for men over 45 years of age. At > that point their *FREE* testosterone level drops radically and the > result can manifest itself as depression. SSRI’s will lower it further, > causing more depression – as well as adding severe unhappiness with the > sexual dysfunction. The doctor will often increase the dosage or use > something even stronger, until the mood-altering effects over-ride the > unhappiness – AKA the "happy eunuch". > Zoloft is particularly bad. If you take a dose that’s adequate for the > job, it’ll do a job on you. > From one pharmaceutical database: > During initial clinical trials, sexual dysfunction manifested primarily > as ejaculation dysfunction > (ejaculatory delay ) and orgasm dysfunction (anorgasmia) was observed in > about 16% of men > and 2% of women treated with sertraline. However, post-marketing > experience has suggested > that the frequency of sexual adverse events is actually much higher. In > fact, many physicians report > an incidence of up to 90% based on their clinical experience. The FDA is > considering changing the > labeling of SSRIs to reflect a higher frequency of drug-induced sexual > adverse events. > From another: >   Home   Site Map   Marketplace   My Medscape   CME Center   Feedback > Help Desk > Side effects for Sertraline Hcl >      Incidence more frequent >          Anxiety >          Decreased Sexual Ability <======= >          Decreased Libido <======= >          Dry Mouth >          Impotence <======= >          Drowsiness >          Dizziness >          Insomnia >          Tiredness/Weakness >          Increased Sweating >          Tremors >          Appetite Loss >          Weight Loss >          Headache >          Nausea >          Gas >          Diarrhea >          Stomach Cramps/Pain >      Incidence less frequent >          Agitated States >          Blurred Vision >          Visual Changes >          Constipation >          Flushing >          Increased Appetite >          Palpitations >          Vomiting >          Nervousness >          Hypomania >          Allergic Dermatitis >          Pruritus >          Hives >          Fever >          Skin Rash >          Allergic Reaction

Thanks Alec, to FIX all of these problems?? I give up. codeee Before you buy.

Response:

My pShrink is now ordering the full set of hormone screening on every male patient over 45 and lower if any libido problems are present. I interpret them for him (name whited out on my copy – doctor/patient confidentiality) and you would be shocked at the number of men who need some hormone adjustments! Fortunately, many men only need lifestyle and dietary adjustments to fully recover. – Hide quoted text — Show quoted text -> > On the same track – what is the real truth about libido and the > sris’ in > > my case zoloft.  Will tapering down to a smaller dose help? > > any advice much appreciated, > > codeee > SSRI’s will often make things worse for men over 45 years of age. At > that point their *FREE* testosterone level drops radically and the > result can manifest itself as depression. SSRI’s will lower it > further, > causing more depression – as well as adding severe unhappiness with > the > sexual dysfunction. The doctor will often increase the dosage or use > something even stronger, until the mood-altering effects over-ride the > unhappiness – AKA the "happy eunuch". > Zoloft is particularly bad. If you take a dose that’s adequate for the > job, it’ll do a job on you. > From one pharmaceutical database: > During initial clinical trials, sexual dysfunction manifested > primarily > as ejaculation dysfunction > (ejaculatory delay ) and orgasm dysfunction (anorgasmia) was observed > in > about 16% of men > and 2% of women treated with sertraline. However, post-marketing > experience has suggested > that the frequency of sexual adverse events is actually much higher. > In > fact, many physicians report > an incidence of up to 90% based on their clinical experience. The FDA > is > considering changing the > labeling of SSRIs to reflect a higher frequency of drug-induced sexual > adverse events. > From another: >   Home   Site Map   Marketplace   My Medscape   CME Center   Feedback > Help Desk > Side effects for Sertraline Hcl >      Incidence more frequent >          Anxiety >          Decreased Sexual Ability <======= >          Decreased Libido <======= >          Dry Mouth >          Impotence <======= >          Drowsiness >          Dizziness >          Insomnia >          Tiredness/Weakness >          Increased Sweating >          Tremors >          Appetite Loss >          Weight Loss >          Headache >          Nausea >          Gas >          Diarrhea >          Stomach Cramps/Pain >      Incidence less frequent >          Agitated States >          Blurred Vision >          Visual Changes >          Constipation >          Flushing >          Increased Appetite >          Palpitations >          Vomiting >          Nervousness >          Hypomania >          Allergic Dermatitis >          Pruritus >          Hives >          Fever >          Skin Rash >          Allergic Reaction > Thanks Alec, > to FIX all of these problems?? I give up. > codeee > Before you buy.

Response:

On the same track – what is the real truth about libido and the sris’ in my case zoloft.  Will tapering down to a smaller dose help? any advice much appreciated, codeee Before you buy.

Response:

> On the same track – what is the real truth about libido and the sris’ in > my case zoloft.  Will tapering down to a smaller dose help? > any advice much appreciated, > codeee

SSRI’s will often make things worse for men over 45 years of age. At that point their *FREE* testosterone level drops radically and the result can manifest itself as depression. SSRI’s will lower it further, causing more depression – as well as adding severe unhappiness with the sexual dysfunction. The doctor will often increase the dosage or use something even stronger, until the mood-altering effects over-ride the unhappiness – AKA the "happy eunuch". Zoloft is particularly bad. If you take a dose that’s adequate for the job, it’ll do a job on you. From one pharmaceutical database: During initial clinical trials, sexual dysfunction manifested primarily as ejaculation dysfunction (ejaculatory delay ) and orgasm dysfunction (anorgasmia) was observed in about 16% of men and 2% of women treated with sertraline. However, post-marketing experience has suggested that the frequency of sexual adverse events is actually much higher. In fact, many physicians report an incidence of up to 90% based on their clinical experience. The FDA is considering changing the labeling of SSRIs to reflect a higher frequency of drug-induced sexual adverse events. From another:   Home   Site Map   Marketplace   My Medscape   CME Center   Feedback   Help Desk Side effects for Sertraline Hcl      Incidence more frequent          Anxiety          Decreased Sexual Ability <=======          Decreased Libido <=======          Dry Mouth          Impotence <=======          Drowsiness          Dizziness          Insomnia          Tiredness/Weakness          Increased Sweating          Tremors          Appetite Loss          Weight Loss          Headache          Nausea          Gas          Diarrhea          Stomach Cramps/Pain      Incidence less frequent          Agitated States          Blurred Vision          Visual Changes          Constipation          Flushing          Increased Appetite          Palpitations          Vomiting          Nervousness          Hypomania          Allergic Dermatitis          Pruritus          Hives          Fever          Skin Rash          Allergic Reaction

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Question:

: : : : California is <really> out there?  this all gets rather abstract at times ….. :   or was it acute, yes acute, acute brit named anne. ttfn : : : : : — : Anne Marshall : : : :

Response:

. . . Never   again to   speak            freely to   speak     at       all Never   again     to       speak to him  . . . Safe at last . . . — Anne Marshall          

Response:

Anne (with the perfect name): I haven’t the slightest idea what your post means, the significance is yours alone to embrace, I do feel it is important to you that you sent it across the Atlantic to land here in California, and many other places.  Whats up Anne with the perfect name, I bet Mr. Marshall was blessed with less than a perfect name, but nevermind he was rewarded with Anne, I have fallen in love with a name, is this in the DSMlV I wonder? ;-o) Regards, Vern

Response:

> Anne (with the perfect name): > I haven’t the slightest idea what your post means, the significance > is yours alone to embrace, I do feel it is important to you that > you sent it across the Atlantic to land here in California, and many > other places.  Whats up Anne with the perfect name, I bet Mr. > Marshall was blessed with less than a perfect name, but nevermind > he was rewarded with Anne, I have fallen in love with a name, is > this in the DSMlV I wonder? ;-o) > Regards, > Vern

Pobody’s nerfect, as they say Vern ….. Toying with verse at the wrong time of day, tired of having my head bitten off for saying the wrong thing at the wrong time (? to the wrong person) …. figuring if I say nothing then there will be <no> cause for the anger (that I can’t cope with) –  just feel like I should disappear. I don’t think this has <anything> to do with <any> diagnosis….. wierd.       He is on meds that he forgets to take and I need to be nursey to "remind" him to take (the paroxetine) …. if I <don’t> nurse him I get the payback . <I> am on no meds and haven’t been since xmas ….  surviving …… but sometimes it seems only just …. California is <really> out there?  this all gets rather abstract at times ….. — Anne Marshall      

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Question:

Thanks for the information.I got a lot out of the article.It not mention the newer bipolar meds. Such as Lamictal and Neurotin.But I realize they have not been approved by the FDA                                                                         Thanks,Still Bipolar Susan.        

Response:

Great article, Keith – thanks! BiPolarGnu  AKA  Richard

| >Two-thirds of bipolar episodes begin with depression; whenever you see a person who is depressed, you should ask | >yourself: ‘Is this person going to be bipolar?’ | | http://www.wpic.pitt.edu/stanley/bipolar2.htm | | This will answer many questions for newbies and lend new perspectives for the | oldies. | | >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>

Response:

Keith: Thanks for the reminder on the Stanley papers. I had reviewed them earlier this summer and I read some of this, but probably should print the whole thing out for future reference. First, it’s amazing to me personally that so many pdocs dx depression from the get-go when both the APA and the Stanley Center adamantly insist the opposite, i.e, first suspect bipolar disorder in patients presenting as "depressed". If a couple of my other pdocs had been up to speed on some of this, it probably would’ve saved me a whole lot of time and anguish. Secondly, Jim "You used me like an ashtray heart, hid me behind the curtain, waited for me to go out…" Captain Beefheart, "Ashtray Heart"

Response:

Keith: Thanks for the reminder on the Stanley papers. I had reviewed them earlier this summer and I read some of this, but probably should print the whole thing out for future reference. First, it’s amazing to me personally that so many pdocs dx depression from the get-go when both the APA and the Stanley Center adamantly insist the opposite, i.e, first suspect bipolar disorder in patients presenting as "depressed". If a couple of my other pdocs had been up to speed on some of this, it probably would’ve saved me a whole lot of time and anguish. Secondly, Jan Fawcett’s comments on calcium channel blockers piqued my interest, as my pdoc just prescribed a CCB (Nifedipine?) as a safeguard against me vapor-locking due to a bad MAOI reaction. Any more on them being used as MSs?  I’m also tempted to ask the pdoc to try me on lithium…I’ve been depakote-free for over a month now. My first experience with lithium probably doesn’t count, as I was taking so damn many pmeds at the time and was not prepared for any of the side efx I encountered. Thirdly, isn’t it interesting that MAOIs are being used heavily again? Some of the Stanley folk seem to be saying that MAOIs should be used as a first-line antidepressant, rather than the SSRIs which seemed to be the norm in the past 6 years or so. Jim "You used me like an ashtray heart, hid me behind the curtain, waited for me to go out…" Captain Beefheart, "Ashtray Heart" Jim "You used me like an ashtray heart, hid me behind the curtain, waited for me to go out…" Captain Beefheart, "Ashtray Heart"

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Question:

I must give Viscount credit for the link that eventually led to this one. You might have to register if you want to see the source, I’m not sure. I registered to get on one site, then linked out to another, then to another, so who knows. http://www.priory.com/pharmol/gingko.htm             Long Term Safety and Efficacy of Ginkgo Biloba Extract in the Treatment of Anti-                               Depressant-Induced Sexual Dysfunction                                          Alan Jay Cohen,M.D. ,                            Diplomate of the American Board of Psychiatry and Neurology,                         Assistant Clinical Professor of Psychiatry at the University of California,                                             San Francisco                      Introduction                                  Methods                                           Results                                                    Discussion                                                                References Introduction: Recent reports have described a new treatment approach for antidepressant-induced sexual dysfunction (ASD)(Cohen, 1996,1997). The discovery of Ginkgo biloba extract’s (GBE) ability to reverse antidepressant-induced sexual dysfunction was reported in patients studied over a 6-8 week period. No long term observations have been made for safety and efficacy in patients taking Ginkgo biloba extract (GBE) for ASD. The experience of five patients who have used GBE for the treatment of ASD safely and effectively over 24 months is described. Methods Five patients treated for DSM-IV diagnosis of Depression with an SSRI (fluoxetine or sertraline) developed sexual dysfunction during the course of their treatment. The three men in the study reported anorgasmia, decreased libido, and erectile failure. The two women had anorgasmia, delayed orgasm and decreased libido. Each patient was started on a course of GBE 60 mg. (50:1 extract) twice a day. There were no contraindications for the use of GBE, such as use of anticoagulants, coagulopathy,nor allergy to GBE. Doses were titrated to 120 mg. twice a day over a 4 week period. Patients were assessed by clinical interview and subject reporting on the following parameters: change in libido, ability to achieve orgasm, and erectile competence. Results Sexual dysfunction was effectively reversed by GBE 240 mg. per day in each patient. Each patient chose to continue the treatment for an open ended period with clinical monitoring of symptoms. Three patients described brief periods of discontinuation of the GBE with a concomitant return of the ASD. The male patients,ages 45, 42, and 38, each had a single episode of non- psychotic major depression. The women, 48 and 49, had recurrent, unipolar depression, non-psychotic. Both women also had Hashimoto’s thyroiditis. Their thyroid indices were normal on replacement T-4. There were no other medical conditions, nor substance abuse problems. Adverse reactions to the GBE were minimal and did not disrupt the treatment. Some gastro- intestinal complaints and lightheadedness were reported. No abnormal bleeding nor bruising occurred. Discussion: GBE has been used for centuries in traditional Chinese medicine. It has recently been described to be beneficial to dementia patients in a 52 week study (Lebars, et al 1997). Cohen(1997) described its use in the treatment of ASD. This is the first documented report of the long term safety and efficacy of GBE in the treatment of ASD. The mechanism of action of GBE involves inhibition of platelet- activating factor(PAF), prostaglandin agonist effects, and neuroreceptor modulation( Braquet 1991, Kleijnen !992). Conclusion: ASD is a major problem in clinical practice(Gitlin 1997). Treatment compliance may suffer with resultant morbidity and mortality. In this small series of patients GBE appears to be a safe and effective long term remedy for ASD. However, further controlled trials are recommended. References: 1. Cohen, A.(1996) "Treatment of Antidepressant- Induced Sexual Dysfunction with Ginkgo Biloba Extract" New Research Report from The Proceedings of The American Psychiatric Association Annual Meeting Abstract #716 . 2. Cohen, A., Bartlik, B. (1997) " Treatment of Sexual Dysfunction with Ginkgo Biloba Extract" Scientific Reports -Paper Session from The Proceedings of The APA Annual Meeting . 3. LeBars, P., et al. (1997) "A Placebo-Controlled, Double-Blind, Randomized Trial of an Extract of Ginkgo Biloba for Dementia" JAMA; 278: 1372-1332. 4.Braquet, P. Hosford,D.(1991) "Ethnopharmacology and the Development of Natural PAF Antagonists as Therapeutic Agents" J. Ethno- pharmacology, ; 32:135-139. 5. Kleijnen,J. , Knipschild, P. (1992) "Ginkgo Biloba" Lancet ; 340:1136-39. 6. Gitlin, M. (1997) "Sexual Side Effects of Psychotropic Medications" in Psychiatric Clinics of North America , Annual of Drug Therapy vol. 4 pg. 61-90. .

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Would 60 mg 4 times a day or 80mg 3 times be more effective that 120 mg twice a day ? Anyone ?? – Hide quoted text — Show quoted text -> I must give Viscount credit for the link that eventually led to this one. You > might have to register if you want to see the source, I’m not sure. I registered > to get on one site, then linked out to another, then to another, so who knows. > http://www.priory.com/pharmol/gingko.htm >             Long Term Safety and Efficacy of Ginkgo Biloba Extract in the > Treatment of Anti- >                               Depressant-Induced Sexual Dysfunction >                                          Alan Jay Cohen,M.D. , >                            Diplomate of the American Board of Psychiatry and > Neurology, >                         Assistant Clinical Professor of Psychiatry at the > University of California, >                                             San Francisco >                      Introduction >                                  Methods >                                           Results >                                                    Discussion References > Introduction: > Recent reports have described a new treatment approach for > antidepressant-induced sexual dysfunction > (ASD)(Cohen, 1996,1997). > The discovery of Ginkgo biloba extract’s (GBE) ability to reverse > antidepressant-induced sexual dysfunction > was reported in patients studied over a 6-8 week period. No long term > observations have been made for > safety and efficacy in patients taking Ginkgo biloba extract (GBE) for ASD. > The experience of five patients who have used GBE for the treatment of ASD > safely and effectively over 24 > months is described. > Methods > Five patients treated for DSM-IV diagnosis of Depression with an SSRI > (fluoxetine or sertraline) developed > sexual dysfunction during the course of their treatment. The three men in the > study reported anorgasmia, > decreased libido, and erectile failure. The two women had anorgasmia, delayed > orgasm and decreased > libido. Each patient was started on a course of GBE 60 mg. (50:1 extract) twice > a day. > There were no contraindications for the use of GBE, such as use of > anticoagulants, coagulopathy,nor allergy > to GBE. > Doses were titrated to 120 mg. twice a day over a 4 week period. Patients were > assessed by clinical > interview and subject reporting on the following parameters: change in libido, > ability to achieve orgasm, and > erectile competence. > Results > Sexual dysfunction was effectively reversed by GBE 240 mg. per day in each > patient. Each patient chose to > continue the treatment for an open ended period with clinical monitoring of > symptoms. Three patients > described brief periods of discontinuation of the GBE with a concomitant return > of the ASD. The male > patients,ages 45, 42, and 38, each had a single episode of non- psychotic major > depression. The women, > 48 and 49, had recurrent, unipolar depression, non-psychotic. Both women also > had Hashimoto’s thyroiditis. > Their thyroid indices were normal on replacement T-4. > There were no other medical conditions, nor substance abuse problems. > Adverse reactions to the GBE were minimal and did not disrupt the treatment. > Some gastro- intestinal > complaints and lightheadedness were reported. No abnormal bleeding nor bruising > occurred. > Discussion: > GBE has been used for centuries in traditional Chinese medicine. It has recently > been described to be > beneficial to dementia patients in a 52 week study (Lebars, et al 1997). > Cohen(1997) described its use in > the treatment of ASD. This is the first documented report of the long term > safety and efficacy of GBE in the > treatment of ASD. The mechanism of action of GBE involves inhibition of > platelet- activating factor(PAF), > prostaglandin agonist effects, and neuroreceptor modulation( Braquet 1991, > Kleijnen !992). Conclusion: > ASD is a major problem in clinical practice(Gitlin 1997). Treatment compliance > may suffer with resultant > morbidity and mortality. In this small series of patients GBE appears to be a > safe and effective long term > remedy for ASD. However, further controlled trials are recommended. > References: > 1. Cohen, A.(1996) "Treatment of Antidepressant- Induced Sexual Dysfunction with > Ginkgo Biloba Extract" > New Research Report from The Proceedings of The American Psychiatric Association > Annual Meeting > Abstract #716 . > 2. Cohen, A., Bartlik, B. (1997) " Treatment of Sexual Dysfunction with Ginkgo > Biloba Extract" Scientific > Reports -Paper Session from The Proceedings of The APA Annual Meeting . > 3. LeBars, P., et al. (1997) "A Placebo-Controlled, Double-Blind, Randomized > Trial of an Extract of Ginkgo > Biloba for Dementia" JAMA; 278: 1372-1332. > 4.Braquet, P. Hosford,D.(1991) "Ethnopharmacology and the Development of Natural > PAF Antagonists as > Therapeutic Agents" J. Ethno- pharmacology, ; 32:135-139. > 5. Kleijnen,J. , Knipschild, P. (1992) "Ginkgo Biloba" Lancet ; 340:1136-39. > 6. Gitlin, M. (1997) "Sexual Side Effects of Psychotropic Medications" in > Psychiatric Clinics of North > America , Annual of Drug Therapy vol. 4 pg. 61-90. .

Share what you know. Learn what you don’t.

Response:

Question:

Hi, > Could I have suggestions.  My Prozac is no longer working but when it did > it was wonderful.  Is there an additional med that could be added to give > it a boost.  Going to the pdoc on Wednesday.  Want to have some > suggestions.

Are you taking a MS along with it? Perhaps you can  discuss this with your pdoc on Wed. Peace, — Reach beyond your grasp!

Response:

Thanks for the reply.  That might very well be the answer; however, I would like to have a drug (mood stabilizer) that has few side effects.  That way I could continue with the Prozac.  The first thing that goes when I become depressed is my ability to sleep and Prozac was great for that. Please write back. Thanks in advance for your response.  May God Richly Bless As You Continue Your Journey in Life Flourish99

Response:

Hi, Could I have suggestions.  My Prozac is no longer working but when it did it was wonderful.  Is there an additional med that could be added to give it a boost.  Going to the pdoc on Wednesday.  Want to have some suggestions. Thanks in advance for your response.  May God Richly Bless As You Continue Your Journey in Life Flourish99

Response:

When Prozac stopped working for me, pdoc put me on Paxil. It worked for me. Good luck.                            Ralph

– Hide quoted text — Show quoted text -> Hi, > Could I have suggestions.  My Prozac is no longer working but when it did it > was wonderful.  Is there an additional med that could be added to give it a > boost.  Going to the pdoc on Wednesday.  Want to have some suggestions. > Thanks in advance for your response.  May God Richly Bless As You Continue Your > Journey in Life > Flourish99

Response:

1st, tell your Pdoc that this happened, it does occasionally happen that a med loses its effectiveness!  There are a number of other SSRIs, not to mention other families of antidepressants.  You might also ask your Pdoc if the addition of a small dose of mood stabilizer might help.  But first do call your Pdoc soonest!!! – Neil – – Hide quoted text — Show quoted text – >When Prozac stopped working for me, pdoc put me on Paxil. >It worked for me. Good luck.                            Ralph > Hi, > Could I have suggestions.  My Prozac is no longer working but when it did >it > was wonderful.  Is there an additional med that could be added to give it >a > boost.  Going to the pdoc on Wednesday.  Want to have some suggestions. > Thanks in advance for your response.  May God Richly Bless As You Continue >Your > Journey in Life > Flourish99

Response:

Question:

I saw my pdoc today, i was having some side effects from prozac, she switched me to paxil 20mg and kept my depakote the same 750mg at nite…can anyone tell me what i might expect with the paxil, this is a new one for me..thanks mary

Response:

> I saw my pdoc today, i was having some side effects from prozac, she switched > me to paxil 20mg and kept my depakote the same 750mg at nite…can anyone tell > me what i might expect with the paxil, this is a new one for me..thanks

Hi Mary, Welcome to ASDM. Good to have you here with us! Paxil is an SSRI like Prozac. It should not be taken with alcohol. Serum sodium levels should be monitored. Side effects which may occur: NOTE – everyone is different – this doesn’t mean you will experience any off  the following: CNS: Insomnia, trmor, somnolence,dizziness, headache.confusion, anxiety. Cardioivascular: Palpitations, postural hypotension (decrease in BP while changing positions) GI : dry moth, nausea, consti[ation, diarrhea, vomiting Skin: rash, itching Good luck. Peace GU: difficulty with orgasm. Reach beyond your grasp!

Response:

> I saw my pdoc today, i was having some side effects from prozac, she switched > me to paxil 20mg and kept my depakote the same 750mg at nite…can anyone tell > me what i might expect with the paxil, this is a new one for me..thanks > mary

In my case, Paxil was the alternative to prozac after prozac made me "too aggressive". Paxil has killed my libido, almost totally; but for me that is no problem. No lady in my life. P-doc says that he will take care of that problem if I have a lady and it becomes a problem for me. Ralph

Response:

> >problem. No lady in my life. > Hope you find someone Ralph

So do I.                        Ralph

Response:

>I saw my pdoc today, i was having some side effects from prozac, she switched >me to paxil 20mg and kept my depakote the same 750mg at nite…can anyone tell >me what i might expect with the paxil, this is a new one for me..thanks

My former pdoc said that (generally) that the SSRIs (that were available at that time) went from stimulating to sedating as follows:         Prozac (most stim) => Zoloft => Paxil She also said (not using this exact term), "YMMV." –C. — IMPORTANT: Remove the edible part of the E-mail address before replying.

Response:

>Side effects which may occur: NOTE – everyone is different – this >doesn’t mean you will experience any off  the following: >GI : dry moth, nausea, consti[ation, diarrhea, vomiting

Dry moth? Does that mean you’ll have a "buggy" feel? Also, a [roblem with consti[ation can be a real [ain in the butt! — IMPORTANT: Remove the edible part of the E-mail address before replying.

Response:

be careful… despite whatever sedating effects some ssri might have–it can still cause a bp problems… what i mean by this.. is just keep a close eye on yourself and call the do if anything unusual happens.. as usual.. alexia who went manic immeadiately on 10mg paxil – Hide quoted text — Show quoted text – >I saw my pdoc today, i was having some side effects from prozac, she switched >me to paxil 20mg and kept my depakote the same 750mg at nite…can anyone tell >me what i might expect with the paxil, this is a new one for me..thanks >mary

Response:

I was on paxil, The first two weeks I yawned a lot, My mouth hurt at the end of the day, I decided to stop taking them two or three weeks later, they did nothing for me.  My Depakote is 1000 mg a day. Try what your doctor gave you, they may work great for you.

Response:

Question:

> > >> Associated with lowered blood pressure, dizziness, blurred vision, > anxiety > >> attacks, increased libido and priapism. > PRIPISM YES.  TRAZADONE BEWARE GUYS. > I have had an erection since June this year No shit.  I have had three > operations and now the BIG chease uroligist in Canada says cut the blood > flow and NO SEX EVER AGAIN.  I am a bunny and you know what Bunnys klike > to do well that was not acceptable.  So the big cheese guy says well

[snip] Are you going anywhere near Cindi’s home in your journeys. Aurora *        *       *    *      *      *      *        *   *       *    *    *   *    *   *        Aurora  *   *     *     *     *      * *     *   *    *       *   *     *   *      *     *   *   *    *  *

Response:

> >> Associated with lowered blood pressure, dizziness, blurred vision, > anxiety >> attacks, increased libido and priapism.

PRIPISM YES.  TRAZADONE BEWARE GUYS. I have had an erection since June this year No shit.  I have had three operations and now the BIG chease uroligist in Canada says cut the blood flow and NO SEX EVER AGAIN.  I am a bunny and you know what Bunnys klike to do well that was not acceptable.  So the big cheese guy says well Gangarine and aputation soon.  I say to hell with that.  He then says cut the blood flow and no sex or death.  Well he is talking to mister suicide, lets see 12 or more attempts and good ones at that last year alone.  So I say death. Now I am told i have to have as much sex as I can to try and "wear it out" because each orgasm realeses hormones to bring it down.  God it is crazy. But its not dead yet and it never quits.  So at times it is an advatage he he he well you have to have some humor about it. Now the big cheese says its not the Trazadone YOU ARE JUST MANIC and HYPER sexual.  yea blame every thing on being BP.  I get pimples also is that a BP thing? Sorry for my long posts Its just me I get carried away on some subjucts.The Energizer Bunny who got his name because no matter how many OD’s I have had or how many or how close i have been to death or how much damage I get with each OD I just keep going and going. Now with the priapism the name is even more apropriat. The Energizer Bunny hanging on and fighting with all his Bunny stength. Lyle    (Hey there’s those wonderful – Hide quoted text — Show quoted text -> words >> again…..oh my oh my oh my..) >Nasty side effects to be sure. > Oh those nasty side effects….nasty nasty nasty.  I’m still a nurse…let > me take care of them… hey…Ever think of opening a clinic just for > treatment of those nasty side effects?  Ooops… talking out loud again.

Response:

Hi Cindy, I am proud of you not taking the SJW. You do sound hypomanic but I know you love to feel that way. Two datwes today? How are you ever….well, nevermind Please take the Lithium as it was ordered, okay? Peace, — Reach beyond your grasp!

Response:

I hope you don’t take the trazodone anymore, lyle! GreetinX        X        X       Bas                     DE  DIGITALE  STAD

Response:

my posts i’me sure are irrelevant or boring or annoying to many, and i hope you all ignore them. i over-reacted to LYNDA. in fairness, i should have explained it more fully (neoropsych exam) in original post.  i’m certain many viewers aren’t familiar with them.  LYNDA i would have expected to, based on what she says about herself.   at least, if you’re not certain, don’t assume it’s the stuff we talk to psychiatrists about. psychology is another world with its own set of diagnostic tests and treatments.  i intended to convey that I myself was distraught with my prognosis.  it was new and different information from that i’ve seen for years on psychiatrist’s record. this pertained to head injury. lny

Response:

Another interesting perspective on why mood stabilizers are important! Thanks for your input, Chris. — Kath From here on my branch I can choose to plunge or soar. I think I shall sit a while longer. <snipped for brevity (so I can post)> – Hide quoted text — Show quoted text -> Mood controllers are like fluid added to the compass. ADs are like > magnets pulling it off to one side. > — > Department of Artificial Intelligence,    Edinburgh University > 5 Forrest Hill, Edinburgh, EH1 2QL, UK                DoD #205 >        http://www.dai.ed.ac.uk/daidb/people/homes/cam/

Response:

> – > Indications: Moderately severe to severe depressions, especially those with > vital signs. LOL!!!!! > Contra-indications: Panic disorder, liver-function disorders, recuperation- > fase of myocardial infarct…… If you read below…. I can see why.

 Interesting about panic disorders. > Side effects: Priapism   (Hmmm……sneak this into my boyfriends… > uh….just thinking outloud folks… hehehe) No fun actually. > Causes strong increase in Norepinephrine (=noradrenal) release.

Only one neurotransmitter here? > Associated with lowered blood pressure, dizziness, blurred vision, anxiety > attacks, increased libido and priapism.  (Hey there’s those wonderful words > again…..oh my oh my oh my..)

Nasty side effects to be sure. Peace, — Reach beyond your grasp!

Response:

>> Associated with lowered blood pressure, dizziness, blurred vision, anxiety > attacks, increased libido and priapism.  (Hey there’s those wonderful words > again…..oh my oh my oh my..) >Nasty side effects to be sure.

Oh those nasty side effects….nasty nasty nasty.  I’m still a nurse…let me take care of them… hey…Ever think of opening a clinic just for treatment of those nasty side effects?  Ooops… talking out loud again.

Response:

                    DE  DIGITALE  STAD Op 17 Feb 1999, Chris Malcolm schreef: >If I am hypomanic then why isn’t the lithium keeping me from being so.   I <snip> > Mood controllers are like fluid added to the compass. ADs are like > magnets pulling it off to one side.

It’s a nice way to put it, but it’s not the exact way it works. The truth is; often when the depression disappears, the mania does as well, in that case an AD can act stabilizing on mood. I agree with you at that this is not the case with dear Cindy. > — > Department of Artificial Intelligence,    Edinburgh University > 5 Forrest Hill, Edinburgh, EH1 2QL, UK                DoD #205 >        http://www.dai.ed.ac.uk/daidb/people/homes/cam/

GreetinX        X        X       Bas

Response:

- Indications: Moderately severe to severe depressions, especially those with vital signs. hahahaha…. Those without vital signs are usually termed… DEAD… and I doubt the dead are very depressed.  : )  But then again…..If I were dead…I’d be depressed.  LOL Contra-indications: Panic disorder, liver-function disorders, recuperation- fase of myocardial infarct…… If you read below…. I can see why. Side effects: Priapism   (Hmmm……sneak this into my boyfriends… uh….just thinking outloud folks… hehehe) Causes strong increase in Norepinephrine (=noradrenal) release. Associated with lowered blood pressure, dizziness, blurred vision, anxiety attacks, increased libido and priapism.  (Hey there’s those wonderful words again…..oh my oh my oh my..)

Response:

                    DE  DIGITALE  STAD Op Thu, 18 Feb 1999, Cindy schreef: > – > Indications: Moderately severe to severe depressions, especially those with > vital signs. > hahahaha…. Those without vital signs are usually termed… DEAD… and I > doubt the dead are very depressed.  : )  But then again…..If I were > dead…I’d be depressed.  LOL

LOL! Vital signs in depression. That means things like the typical sleep disturbance, look it up in DSM IV if you want to know more. > Contra-indications: Panic disorder, liver-function disorders, recuperation- > fase of myocardial infarct…… If you read below…. I can see why. > Side effects: Priapism   (Hmmm……sneak this into my boyfriends… > uh….just thinking outloud folks… hehehe)

LOL! That probably would work, but the taste is kinda horrid, so I’m wondering in what thing other than tea you’d like to sneak it into. Aren’t your boyfriends libidos high enough. Horny Hypo Cindy talking again, glad to have you back! LOL! > Causes strong increase in Norepinephrine (=noradrenal) release. > Associated with lowered blood pressure, dizziness, blurred vision, anxiety > attacks, increased libido and priapism.  (Hey there’s those wonderful words > again…..oh my oh my oh my..)

LOL! HHCindy again! GreetinX        X        X       Bas

Response:

>Op 17 Feb 1999, Chris Malcolm schreef: > >If I am hypomanic then why isn’t the lithium keeping me from being so.   I > Mood controllers are like fluid added to the compass. ADs are like > magnets pulling it off to one side. >It’s a nice way to put it, but it’s not the exact way it works. >The truth is; often when the depression disappears, the mania does as >well, in that case an AD can act stabilizing on mood.

Of course. I was describing an ideal world of perfect ADs and perfect mood controllers, to clarify the issues. In this real world nothing is perfect, not even drugs , and some mood controllers have some AD activity too, some ADs have some mood controlling activity, and they all have other side effects too. It is also the case that BPs are not all the same, fast cyclers and slow cyclers react differently to the drugs, for example. My compass analogy sets out the difference between an idealised AD and an idealised mood controller, to make clear their different effects and manner of working. — Department of Artificial Intelligence,    Edinburgh University 5 Forrest Hill, Edinburgh, EH1 2QL, UK                DoD #205        http://www.dai.ed.ac.uk/daidb/people/homes/cam/

Response:

(((Cindy))), Hang in there, I really do believe SJW is making you more unstable than you already are, it’s your choice of course, but you might want to consider this. You’re not dead, you’re one tough babe & you’ll probably outlive us all, just hang in there… GreetinX        X        X       Bas                     DE  DIGITALE  STAD

Response:

                    DE  DIGITALE  STAD Op Tue, 16 Feb 1999, Cindy schreef: > You are a regular capgun. > — >   O  ooo   Cindy >          O

LOL!

Response:

here I send you more info on Herbal Happiness, it might be something for you: A Herbal Antidepressant. Hypericum perforatum ==> Possible MAO inhibiting activity (disputed)                          SRI activity                          NARI activity                          DARI activity                          Active by itself in .3 – 1.8 gr range as AD.                          Proven herbal anti-depressant. Corynanthe yohimbe   ==> By

Question:

>SJW is not recommended for BP disorder as it may trigger a mania.

My BP wife has had a number of manias triggered by ADs, so she is susceptible to this. However, she has taken SJW for more than enough time to trigger a mania, if it was going to do that, and it has shown no signs at all of doing that. In addition, all of the several prescribed ADs she has taken have had the effect of speeding up the cycle period of her mood swings by about 20% (in fact, I suspect that this is how they lift derpessions, by simply shortening the cycle period). SJW, however, does not have this effect on her, so either it is not much as (for her) as an AD, or else it works by a different mechanism. I have not seen any reports which have found SJW to trigger mania. I suspect this is simply the usual general AD caution applied to SJW, incorrectly, I suspect. — Department of Artificial Intelligence,    Edinburgh University 5 Forrest Hill, Edinburgh, EH1 2QL, UK                DoD #205        http://www.dai.ed.ac.uk/daidb/people/homes/cam/

Response:

>>SJW is not recommended for BP disorder as it may trigger a mania. Ditto >for Ginseng. >The active ingredient in SJW has some MAO inhibitor characteristics, >including a tendency to the tyramine reaction ("cheese reaction").

However, it does not have enough MAO inhib to explain its effect, and it has been used very extensively by cheese-eaters in both Germany and Britain for many years without anyone noticing the usual bad MAO inhib effects. One can therefore conclude that either there is something else in it to counteract these effects, or the MAO inhib activity is simply too small to be significant. There is a tendency for US psychiatrists to suppose that drug use and research conducted outside the US is conducted by stupid foreigners who don’t count, and when faced with lots of non-US research, even non-English-language research (as in the case with SJW), they like to stop their patients asking embarrassing questions by spreading scare stories. That’s not to say that SJW is a good AD for BPs to use. While it has shown efficacy in plain unipolar depression (and definitely works for me), it’s utility in BP has yet to be established. Unfortunately those BPs who don’t want to take "psychiatric drugs", but only "natural plant extracts which don’t have nasty poisonous side effects" tend to gravitate to SJW as one of the few good non-prescription psychotropic medications. Two others are coffee and tobacco, which as we know *do* have certain unpleasant side-effects, despite being derived from "natural plants". Unfortunately there are no reports of BP having been successfully controlled by any kind of AD, and plenty of ADs making it worse. *If* SJW is any use in BP, it will only be as an adjunct to a mood controller, not as a substitute. — Department of Artificial Intelligence,    Edinburgh University 5 Forrest Hill, Edinburgh, EH1 2QL, UK                DoD #205        http://www.dai.ed.ac.uk/daidb/people/homes/cam/

Response:

>SJW is not recommended for BP disorder as it may trigger a mania. Ditto >for Ginseng.

The active ingredient in SJW has some MAO inhibitor characteristics, including a tendency to the tyramine reaction ("cheese reaction").

Response:

> Hello > Many pharmaceutical antidepressants, particularly the SSRIs, have > adverse effects on sexual functioning in males and females.

Dear Marcella, SJW is not recommended for BP disorder as it may trigger a mania. Ditto for Ginseng. So I don’t know how many responses you may receive. I wanted to take it and my pdoc nixed it in a heartbeat We all need to stick with our pdoc’s recommendations. Peace, Reach beyond your grasp!

Response:

sexual function??? what’s that? sex?? im a born again virgin.. *sigh* – Hide quoted text — Show quoted text – >Hello >Many pharmaceutical antidepressants, particularly the SSRIs, have >adverse effects on sexual functioning in males and females. >I am wondering if anyone out there (male or female) who has taken St. >John’s Wort for some period of time has had any changes in their sexual >function. >The things I would be interested in are: >1. Approximately how long you have been/are taking it (days, weeks, >months, etc.) >2. Did it hinder, improve, or not effect sexual functioning? >3. What did it affect? e.g.: >        a. desire for sex >        b. physical arousal (erection, vaginal secretions) >        c. ability to reach orgasm >4. What condition are you taking it to treat? >5. Are you taking any other prescription or recreational drugs. >This is only an informal poll, but I would greatly appreciate any >anecdotes people may have since little or none seems to be written on >this in the clinical literature. All responses are strictly >confidential. No identification is needed. Thanks! >Sincerely, >Marcello Spinella, Ph.D.

Response:

Question:

Has anyone not gained weight on zyprexa or have been able to control it?I feel great on this drug but my appetite is up.It’s hard to control it but I have to.I finally have hope though that I have found my cocktail thanks to this drug.Does the weight gain taper off orkeep going? TIA

Response:

i stopped taking it–switched to risperdal–before i found out whether or not the weight gain tapers off… i couldn’t deal with it (although it was working)…ive also heard from other people thaat weight gain with zyprexa is common… ??? good luck a – Hide quoted text — Show quoted text – >Has anyone not gained weight on zyprexa or have been able to control it?I feel >great on this drug but my appetite is up.It’s hard to control it but I have >to.I finally have hope though that I have found my cocktail thanks to this >drug.Does the weight gain taper off orkeep going? TIA

Response:

I have been on Zyperxia for about 4 months. It increased my appetite somewhat, but nothing dramatic. Take care.

Love, Leslyn

Response:

I’ve been on Zyprexa for about a year now, and haven’t noticed any weight gain. So maybe I’m one of the lucky ones. It’s worked well for me, after trying Risperdal which I didn’t like for side effects I don’t recall exactly what kind at the moment.  I take 5mg of Zyprexa every night. Susan

Response:

                    DE  DIGITALE  STAD Op 30 Jan 1999, Jagca1 schreef: > Has anyone not gained weight on zyprexa or have been able to control it?I feel > great on this drug but my appetite is up.It’s hard to control it but I have > to.I finally have hope though that I have found my cocktail thanks to this > drug.Does the weight gain taper off orkeep going? TIA

Well, I really did not gain weight, I think, if anything I got stabilized on a certain weight. I rarely experience apetite (read: almost never), but I trie to eat at least twice a day (I don’t always succeed in this), but on 10mg of Zyprexa/day I was hungry all the time, even when my stomach was full, well I guess I gained about 2 kgs, but then I got depressed again (and lost about 6 kgs), I gained the most weight on paroxetine (paxil/seroxat) 8 kgs. But it always seems to be depending on my overall mood (when depressed like 59kgs-underweight-when `normal’, 68kgs, when hypo to manic about 61-65). Zyprexa did increase my apetite chronicly, that means, after 5 months of taking 10mgs every day, my apetite was still huge (yet I don’t seem to care about those feelings when depressed, so I still don’t eat much). Hope this was of any help… GreetinX        X        X       Bas p.s: only quitting Zyprexa seemed to be the solution of feeling apetite…

Response: