SSRIs

Question:

I have a hypomanic reaction to SSRIs. Is there anything out there that doesn’t lead to hypomania in those of us that are prone toward it? Louise

Response:

> I have a hypomanic reaction to SSRIs. > Is there anything out there that doesn’t lead to hypomania in those of > us that are prone toward it? > Louise

I have the same problem with SSRI and tried Serzone (no hypomanic reaction but made me sleep all the time) and Manerix (moclobemide), a good antidepressant with very little side effects that is not available in the US. alias.p

Response:

> I have a hypomanic reaction to SSRIs. > Is there anything out there that doesn’t lead to hypomania in those of > us that are prone toward it? > Louise

I understand that the new direction of anti-depressants, after patents expire soon such as on prozac, will actually be a backwards direction, towards tricyclics. You might explore those, and also consider that wellburtin (is supposed to) effects dopamine rather than seratonin. I believe wellbutrin is more commonly prescribed to patients who might experience (hypo)mania. You also need to discuss these things with your doctor.

Response:

That’s odd since Wellbutrin is definitely one of the speediest of current ADs, often causing insomnia in fact.

Response:

> That’s odd since Wellbutrin is definitely one of the speediest of current ADs, > often causing insomnia in fact.

What’s even more odd, is that neurontin is used as a mood stabilizer, yet causes almost immediate hypomania. They might use it as an anti depressant now, I’m not sure.

Response:

– Hide quoted text — Show quoted text -> I have a hypomanic reaction to SSRIs. > Is there anything out there that doesn’t lead to hypomania in those of > us that are prone toward it? > Louise > I understand that the new direction of anti-depressants, after patents > expire soon such as on prozac, will actually be a backwards direction, > towards tricyclics. You might explore those, and also consider that > wellburtin (is supposed to) effects dopamine rather than seratonin. I > believe wellbutrin is more commonly prescribed to patients who might > experience (hypo)mania. > You also need to discuss these things with your doctor.

I took Wellbutrin a while ago and was so-o-o-o irritable I couldn’t stand myself! Louise

Response:

Question:

Has anyone on this newsgroup attempted to discontinue his or her SSRI by switching to St. John’s Wort? Dr, Hyla Cass, an assistant clinical professor of psychiatry at the UCLA School of Medicine, has authored a book (copyright 1998) in which she promotes the use of St. John’s Wort for depression and has a protocol for switching from an antidepressant to St. John’s Wort. My question is whether anyone has attempted such a trasnsition and were you successful in the switch? I know there is a question of lack of FDA regulation, but several of the name brands (Kira, Movana) are reputable (Kira even being imported from Germany) Thank you very much for any replies.

Response:

Thanks for info bout the book. I stopped the SSRI’s a year ago.. I managed to keep the worse of the black dog at bay, by using vitamins and supplements,  exercise, changing diet to low carb gluten free diet, and rejecting relations with toxic people. If I dont take vitamins and supplements.  or dont exercise or I go off my diet,  or I engage in communications with any Toxic people.. my mood starts deflating quickly.. I been considering trying SJW to see if it will keep my mood stablized even if I do have to deal with say,  toxic people. Right now in my real life..I can choose not to deal with toxics..  but say I go back to work..and their coworkers… I will HAVE to be able to deal with them without such dealings causing my mood to sink.. So, thanks again for name of a helpful book..

– Hide quoted text — Show quoted text -> Has anyone on this newsgroup attempted to discontinue his or her SSRI > by switching to St. John’s Wort? > Dr, Hyla Cass, an assistant clinical professor of psychiatry at the > UCLA School of Medicine, has authored a book (copyright 1998) in which > she promotes the use of St. John’s Wort for depression and has a > protocol for switching from an antidepressant to St. John’s Wort. > My question is whether anyone has attempted such a trasnsition and > were you successful in the switch? > I know there is a question of lack of FDA regulation, but several of > the name brands (Kira, Movana) are reputable (Kira even being imported > from Germany) > Thank you very much for any replies.

Response:

>Has anyone on this newsgroup attempted to discontinue his or her SSRI >by switching to St. John’s Wort? >Dr, Hyla Cass, an assistant clinical professor of psychiatry at the >UCLA School of Medicine, has authored a book (copyright 1998) in which >she promotes the use of St. John’s Wort for depression and has a >protocol for switching from an antidepressant to St. John’s Wort. >My question is whether anyone has attempted such a trasnsition and >were you successful in the switch? >I know there is a question of lack of FDA regulation, but several of >the name brands (Kira, Movana) are reputable (Kira even being imported >from Germany)

St. John’s wort doesn’t work.  There have been several clinical trials and not one has proved conclusively that it works.  Many people here have tried it and eventually went to a doctor for SSRIs.  I tried it for a month or two and it made me feel very strange.  I currently take Effexor and would not try St. John’s wort again.

Response:

Question:

<< The authors foresee an eventual blending of psychiatry and neurology, but what they leave unsaid is the possibility of a breakdown in the distinctions between various forms of mental illness, and ultimately how we perceive it. Dr  >> Thank the lord!!! Merge Psychiatry into Neurology and be done with it…mental illness shall be treated as a brain based physical illness in the future. Eric Steroids caused my depression…prednisone should be used conservatively http://groups.yahoo.com/group/FactsAndFallaciesOfDepression MIBS (Minimally Invasive Brain Stimulation) http://www.musc.edu/psychiatry/fnrd/tms.htm

Response:

"Left unsaid is the possibility of a breakdown in the distinctions between various forms of mental illness." We’ve been told that the new generation of antidepressants act by blocking the reuptake of the neurotransmitter serotonin in the brain, but what precisely is that supposed to mean? In a Medscape article, Thomas Kramer MD is candid enough to admit: "Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical effects of these compounds. We have very little proof, and sometimes very little data, about whether the neurochemical effects that we find have anything to do with the therapeutic effect of the medication." In support of his argument, he cites the antidepressant, tianeptine, available only in Europe, that is a selective serotonin reuptake ENHANCER – ie, it works exactly opposite to SSRIs but with the same therapeutic effect. He speculates both classes of drugs may work because of their action rather than type of action, each succeeding in "jolting" the firing of neurons. To illustrate the principle, Kramer cites a story dating from the golden age of radio when a malfunction in the main transmitter caused CBS to go off the air. When the company

Question:

 In the article below, glutathione and various antidepressants were used to determine a method of treatment for depression. Both glutathione and the antidepressants were able to relieve depression. (Glutathione and the antidepressants were not used in combination with each other) Read about people that were suffering from depression that have used Immunocal to raise their glutathione levels. To define a few words to make the article easier to read. Glutathione: Glutathione is found in cells. The levels of glutathione can vary in the cells. SSRIs, other medications and toxins of all type lower the glutathione levels in your cells. Glutathione is the most important part of the cells when it comes to cleaning out all toxins. Vitamins will not even be absorbed into the cells if the glutathione levels are too low. GSH: GSH is glutathione. Immunocal raises glutathione levels in the cells by presenting the cells with the 3 amino acids necessary for the cells to make glutathione. The 3 amino acids must be presented to the cells in the proper order or sequence for the cells to use them to make glutathione. Substrate: Substance that is acted upon by an enzyme Article Glutathione as a cerebral substrate in depressive behavior. Behavior depression through inescapable foot shock stress in Swiss albino mice was measured on the basis of their performance in an open field test (OFT) and a forced swim test (FST). Glutathione (GSH) and various antidepressants (impipramine, maprotiline, fluvoxamine, trazodone, and alprazolam) were able to, either fully or partly prevent and/or reverse the shock-induced behavioral depression. The Glutathione (GSH) level was measured in the cerebral cortex, cerebellum, brain stem, and the hypothalamus in shocked mice to ascertain a possible correlation between brain GSH and stress-induced depression, under conditions of preshock and postshock antidepressant treatments as well as in the absence of the drugs. There was an appreciable depletion of cortical Glutathione (GSH) in shocked mice that corrected to varying degrees by the different antidepressants. The result suggest a close link between stress-induced behavioral depression, increased monoaminergic utilization, oxidative stress, and brain Glutathione (GSH). Source: Pharmacology Biochemical Behavior 1994 Aug; 48 (4):845-

Response:

> Article > Glutathione as a cerebral substrate in depressive behavior. > Behavior depression through inescapable foot shock stress in Swiss albino mice > was measured on the basis of their performance in an open field test (OFT) and > a forced swim test (FST).

Give me a break.  Just don’t have so many kids then you won’t have so many problems. Sick bastards. Squiggles

Response:

- Hide quoted text — Show quoted text ->> Article >> Glutathione as a cerebral substrate in depressive behavior. >> Behavior depression through inescapable foot shock stress in Swiss albino >mice >> was measured on the basis of their performance in an open field test (OFT) >and >> a forced swim test (FST). >Give me a break.  Just don’t have so many kids >then you won’t have so many problems. Sick bastards. >Squiggles > Your response indicates you dismiss the subject.

My response indicates I don’t like the subject. > Do you know anything about the subject matter.

I can read, and i presume that is why this was posted to a public ng n’est pas? > I dont, but when I come across things I dont know anything about, especially > recommendations or information related to SSRI et al and what I can do about > having taking them with the conseqencces for me of having done so, I want to > know about the information and recommendations etc.

Well, then go ahead and glean the good parts. >  I post them just to see if anyone has knowledge bout this theory or that, this > treatment or that. > I like to hear what you know, if your reply is a result of some knowledge about > this either way, supportive or rejecting.

No, it’s a response to how the results were gotten. I stop there, because whatever profit is gotten from that torture is not something that interests me. It’s morally repugnant to me. Squiggles

Response:

> I completely missed your point, sorry. I will keep the offense taken to such in > mind. > I had no idea what you were replying to, l  thought you were talking bout me, > and  and thought,  then dismissed reminding you I only had one child! > Linda

No Linda, and it’s interesting that your reply should come at the heels of an article by Storm King posted just now, discussing mood and how that effects cyberspace communication and relations — yes, i saw the part about placing animals in a torture situation where they had no choice of escape and had to go through, and thought…. there must be a better way. But my mood of angst at the thought of the animals just got the better of me. Now i know that I take li, and if you ask me all i can say is that Cade used those rabbits to pee, then killed them.  That was many decades ago, and i don’t think they do lithium experiments anymore … ok ok someone is going to find something to make me feel like shit. Squiggles

Response:

– Hide quoted text — Show quoted text -> I completely missed your point, sorry. I will keep the offense taken to such in > mind. > I had no idea what you were replying to, l  thought you were talking bout me, > and  and thought,  then dismissed reminding you I only had one child! > Linda > No Linda, and it’s interesting that your reply should > come at the heels of an article by Storm King posted just now, > discussing mood and how that effects cyberspace communication > and relations — yes, i saw the part about placing animals > in a torture situation where they had no choice of escape and > had to go through, and thought…. there must be a better way. > But my mood of angst at the thought of the animals just got > the better of me. Now i know that I take li, and if you ask me > all i can say is that Cade used those rabbits to pee, then > killed them.  That was many decades ago, and i don’t think > they do lithium experiments anymore … ok ok someone is > going to find something to make me feel like shit. > Squiggles

Vivisection and animal toture is vile and disgusting.. It can be argued in some cases a neccessary evil in life saving research.. much of it however is completely trivial.. Thank goodness most youngsters tend to share your views . animal abusers are increasingly on the defensive .. In the UK one of the chief offenders Huntingdon Life Sciences  needed the Government to step in as no bank would touch them with a bargepole after the widespread and persistent demonstrations against their vile activities. Mental patients too have been subjected to disgusting experimentation in the name of the pursuit of knowledge . Bob

Response:

>Mental patients too have been subjected to disgusting experimentation in the >name of the pursuit of knowledge . >Bob

Goes to show at what pains we will go to feel well…… —–= Posted via Newsfeeds.Com, Uncensored Usenet News =—– http://www.newsfeeds.com – The #1 Newsgroup Service in the World! —–==  Over 80,000 Newsgroups – 16 Different Servers! =—–

Response:

>Mental patients too have been subjected to disgusting experimentation in the >name of the pursuit of knowledge . >Bob > Goes to show at what pains we will go to feel well……

Oh Im not talking about drug trials or anything some of the stuff that went on would truly make you weep at mans inhumanity to man.. Except mental patients were considered less than human and expendable with no-one to care if they lived or died.. as some did. Bob – Hide quoted text — Show quoted text -> —–= Posted via Newsfeeds.Com, Uncensored Usenet News =—– > http://www.newsfeeds.com – The #1 Newsgroup Service in the World! > —–==  Over 80,000 Newsgroups – 16 Different Servers! =—–

Response:

Linda, I’m not going to respond to this post because I believe you are ill right now. The deterioration in your patterns of writing and thought over recent weeks makes that clear to me and to others here. I would have a lot to say if I thought you were in a frame of mind that allowed you to hear it, but since you’re not, I’m not going to argue with you. It seems to make the situation worse, not better, and I want to see you get better.  Until you’re in a healthier condition, this is the only response I’m going to make to you, no matter how much I disagree with what you post and no matter what you say about me or others here. Linda – Hide quoted text — Show quoted text ->> > I completely missed your point, sorry. I will keep the offense taken to >such in >> > mind. >> > I had no idea what you were replying to, l  thought you were talking >bout me, >> > and  and thought,  then dismissed reminding you I only had one child! >> > Linda >> No Linda, and it’s interesting that your reply should >> come at the heels of an article by Storm King posted just now, >> discussing mood and how that effects cyberspace communication >> and relations — >with the bad behaved manics choosing the create the climate and environment >trolling this NG its effected me to think first such was a personal attack, but >then considering the author, I thought maybe not, you might have blinders are >not seeing something so reply with a request to be enlightened, rather than >assume what your first thought was. >So yes, I agree how the climate created by some effects all, even those seeking >to post posts giving hope, totally infected! > yes, i saw the part about placing animals >> in a torture situation where they had no choice of escape and >> had to go through, and thought…. there must be a better way. >> But my mood of angst at the thought of the animals just got >> the better of me. Now i know that I take li, and if you ask me >> all i can say is that Cade used those rabbits to pee, then >> killed them.  That was many decades ago, and i don’t think >> they do lithium experiments anymore … ok ok someone is >> going to find something to make me feel like shit. >> Squiggles >Vivisection and animal toture is vile and disgusting.. >It can be argued in some cases a neccessary evil in life saving research.. >much of it however is completely trivial.. >Thank goodness most youngsters tend to share your views . >animal abusers are increasingly on the defensive .. >In the UK one of the chief offenders >Huntingdon Life Sciences  needed the Government to step in as no bank would >touch them with a bargepole after the widespread and persistent >demonstrations >against their vile activities. >Mental patients too have been subjected to disgusting experimentation in the >name of the pursuit of knowledge . >Many scandals in the US bout using mental patients for experiments, recently >experiements on children been outed! > I think the SSRI experiment unresearched unproved chemical to  millions round >the world not knowing what it really do positively and negatively will go down >in history as one of the biggest scandals ever, when all the truth comes out, >which it will >Linda . >Bob

Response:

Question:

 Dr. prescribed Paxil and Buspar for me today.  I planned on him prescribing Paxil but I was thrown off by him giving me Buspar too. Didn’ t think I was that bad off.  Anyone have any suggestions why or their experiences with 2.  I have GAD, SP and depression.  Also I like to enjoy a few glasses of wine on occasion on weekends and wondering what people experiences have been with combining alcohol with buspar. I have done some reading on Paxil but not buspar so it is kind of scareing me.

Response:

> Paxil is a great antidepressant. Just keep in mind you have to keep taking it > every single day for it to work. Dont listen to all the people on this board > who will trash Paxil and try to get you to not take it.

They have read up on Paxil they are asking about Buspar and its interaction with alcohol They certainly dont want you turning ther inquiry into a political football CLEAN UP YOU ACT ERIC – Hide quoted text — Show quoted text -> Eric > Consumer complaints about psychiatry drug problems should be reported to FDA > Medwatch, ask for Medwatch form 3500.   http://www.fda.gov/medwatch/ > MIBS (Minimally Invasive Brain Stimulation) > http://www.musc.edu/psychiatry/fnrd/tms.htm

Response:

> Dr. prescribed Paxil and Buspar for me today.  I planned on him > prescribing Paxil but I was thrown off by him giving me Buspar too. > Didn’ t think I was that bad off.  Anyone have any suggestions why or > their experiences with 2.  I have GAD, SP and depression.  Also I like > to enjoy a few glasses of wine on occasion on weekends and wondering > what people experiences have been with combining alcohol with buspar. > I have done some reading on Paxil but not buspar so it is kind of > scareing me.

I’ve been using Paxil for three months, and drank three or more drinks four times in one night. At first, I got super drunk, much more than normal, in a pleasant way. Soon, though, I experienced no positive effects of drinking (the Paxil gives me a constant sense of relaxation and loss of inhibitions, at a level that alchol seems unable to increase) and only the negative ones: sleepiness, sickness, dizziness, etc. So I "quit" drinking, but occassionally drink less than one drink per outing. KC

Response:

- Hide quoted text — Show quoted text ->Watch his agitation >and/or agression cause Paxil changes his noradrenaline levels. > This is totally untrue. Paxil does not increase noradrenaline except at the > very highest dosages, say such as 50 mg or above. And even then the amount of > norephinephrine increase is very small. > All SSRIs can cause increased agitation in the first few weeks, as well as > causing increased anxiety. Not just Paxil. This is due to the body adjusting to > the medication. Paxil does not usually make people "aggressive" where did you > hear that at? In the vast majority of folks who take Paxil it makes them less > aggressive actually…more confident, focused and assertive. But it does not > make one "aggressive." > What a bunch of BS. > Eric

I thought you had an appointment for ECT today – i was curious to see the results – ? Squiggles

Response:

> >I thought you had an appointment for ECT today – i was curious >to see the results – ? > Me? You are talking about that Matt Tarbox kid Squiggles. Im not getting ECT > anytime soon. Maybe someday, but not in the plans. > Eric

You’re all talk. Squiggles

Response:

> >I thought you had an appointment for ECT today – i was curious >to see the results – ? > Me? You are talking about that Matt Tarbox kid Squiggles. Im not getting ECT > anytime soon. Maybe someday, but not in the plans.

Honestly I hope the day never comes for you Eric.

Response:

- Hide quoted text — Show quoted text ->eloquently sang the following hymns: >>Paxil is a great antidepressant. Just keep in mind you have to keep taking >it >>every single day for it to work. Dont listen to all the people on this >board >>who will trash Paxil and try to get you to not take it. >>Eric >I will not say he should not take it. For many this is a great drug. But I >would warn him that a small group (how small i wonder) has very negative >results with paxil. I would warn him to watch himself carefully and check >with his friends and family if they perceive a major personality change in >him so that they can keep an eye out for any problems. Watch his agitation >and/or agression cause Paxil changes his noradrenaline levels. I would tell >him to take it easy and make sure tell his docs about any sign of such >behaviour. >And if he/she is experiencing the dark side of Paxil, do not stop taking it >cold turkey, but be sure to work out a plan with doctor to taper off the >stuff, >cause of the horrific withdrawal accompanies many cesstion of paxil if not >done >gradually. >Linda >      /  .  __   _       >      /  | | _| |_ | |                         >     /– | |    |_ | | > Team | AMIGA

Dr. Michael Norden explains in his book that almost all a.d’s can cause aggressive reactions, BUT, that should not in any way prevent them from being a choice. He also explains most doctors tend to start patients on way, way too high of doses, and the "steady-slow" rule tends to work best, no matter what a.d. "All" a.d’s should actually be available in either liquid, or small dose sizes like the tricyclics have to help people ease on to their medication. Dr. Norden also points out all of the hype crap and scaremongering over benzos, and explains they can be very vital in helping calm the nervousness when starting an a.d., for the first few months. Best, Jay

Response:

Question:

I have terrible physical symtpoms (feeling poisoned and just generally sick) every few days.  Docs say I’m healthy and it must be from anxiety and OCD. Buspar did nothing.   Prozac and Zoloft made me feel worse than ever. Valium helps a lot but some days it fails me (I take it daily anyway) and that’s why I need something better.   Suggestions?

Response:

Neurontin, maybe. Its not specific for OCD but from what you described and from my own experience a short trial (two or three weeks) of a medium dosage range 600 to 1800mg might determine if it would be helpful to you.  Also if the Valium is not operating up to par a couple of things you could try is oral GABA tablets to possibly restore somewhat the benificial Valium effect and also I believe some research ( I can’t recall the source) that niacinamide (not the nicotinic acid version of vit. b-3-Niacin) has a benzo receptor influence which might potentiate the valium somewhat hopefully to the point where you will get efficacious benifits from your Meds.(remember,amide form, commonaly in B-complex pills)  No guaranty that this will meet your needs but it is cheap and easy and safe to try. …Except for the Neurontin, its safer than most and easy to try but it aint cheap. If it works for you, if you’re a full responder then it is DEFINITELY worth it.  I can’t give you an opinion on clonipramine (Anafranil) but am leery of all heterocyclics. Luvox (fluvoxamine) can have a decent antidepressant and OCD effect but side effects could be a problem. It varies alot with each person so there is no way to know except to try. If your Doc has DX’d you OCD I doubt there would be any problem in getting a script for it. If I can think of anything else i’ll post it. Good Luck!    J.D.

Response:

How long were you on  Prozac and/or Zoloft?  The SSRIs are the drug of choice for OCD disorders.  If you gave either of them fewer than four weeks, you should try again. JM

– Hide quoted text — Show quoted text -> I have terrible physical symtpoms (feeling poisoned and just generally sick) > every few days.  Docs say I’m healthy and it must be from anxiety and OCD. > Buspar did nothing.   Prozac and Zoloft made me feel worse than ever. > Valium helps a lot but some days it fails me (I take it daily anyway) and > that’s why I need something better.   Suggestions?

Response:

Question:

 Umm..here I sit with a months supply of this rather spooky antidepressant in one hand and all my hopes and fears in another. Being a good net junkie, I decided to check the NG’s to see if there was anything being posted about this stuff. Boy, have I gotten an eyeful from this group. I’ve never been on any medication for depression before; however, I’ve also never been in the situation that I’m currently in before. For just about a year and a half, all that I have that energy to do is look at internet porn and doze off for hours a day. Needless to say, the wife and kiddies aren’t too pleased with this turn of events. I figure that it has cost me about 90 grand in lost salary and just about everything else in self esteem. I won’t go into particulars, but I brought all of this on myself and now I have to dig out somehow. There seems to be some good souls here, so I’ll just jump into the wind and ask my naive question. Will this stuff do me any good? Do the benefits outweigh the bugs or am I stepping onto a roller coaster that may not stop when I want to get off? I would appreciate any sincere comments. Thank You.                           Ward W

Response:

- Hide quoted text — Show quoted text -> Nothing spooky about good old Effexor Ward. Effexor is a great antidepressant > and it will probably change your life for the better, possibly back to normal > and back to working full time. Its probably the strongest modern class > antidepressant and has relatively few side effects. Expect to feel dizzy and > sedated the first week, then possibly really activated for a while and "weird" > feeling. But after its been in your system a few weeks WATCH OUT cause the odds > are its gonna make you feel really really good. You are gonna love Effexor I > bet, once you get over your fear of antidepressants. > Modern antidepressants are all extremely safe Ward. Nothing to be scared of > man. > take care, > Eric > http://groups.yahoo.com/group/FactsAndFallaciesOfDepression > MIBS (Minimally Invasive Brain Stimulation) > http://www.musc.edu/psychiatry/fnrd/tms.htm > FIDO…Fuck It Drive On

Hey Eric, thanks much for the quick response. You know, part of the problem, as I see it, is that I WILL like the stuff. Too much, in fact, to want to get off of it. Also, your description about the first coupla weeks of side effects reminds me too much of all the bad acid that I used to gobble in my youth. May I ask you a personal question? Have you been off anti-depressants for any significant time since you were first prescribed them? If so, what has your experience been with "withdrawal" and subsequent coping in drug free periods? Looking forward to hearing from you again. Best, Ward W

Response:

> Umm..here I sit with a months supply of this rather spooky >antidepressant in one hand and all my hopes and fears in another. Being >a good net junkie, I decided to check the NG’s to see if there was >anything being posted about this stuff. Boy, have I gotten an eyeful >from this group.

I am about to start Effexor too.  I ordered my pills from Canada. I had been taking Wellbutrin but it wasn’t working.  Effexor gets good reviews.  Stay away from the SSRIs. Diablo

Response:

– Hide quoted text — Show quoted text -> Effexor gets >good reviews.  Stay away from the SSRIs. > Diablo, keep your incorrect opinions about SSRIs to yourself please. I have > news for you dude. There is very little difference between low dose Effexor > (37.5 mg-150 mg ) and the SSRIs. Low dose Effexor is basically nothing more > than an extra strength SSRI Diablo. So if you dislike SSRIs Id stay away from > Effexor. > Be careful Diablo, that Effexor is VERY similar to the SSRIs and it might turn > you into a psycho/lunatic/killer/psychopath. I hope you have your guns locked > up when you take the Effexor Diablo. LOL Sheeesh man you are ridiculous.

No Eric you are ridiculous with your lack of knowledge….  trying by aggression ….foul language and pure force of will  to deny others experience, freedom of speech and the free flow of information. You are not a psychiatrist… You have no business telling people they must be drugged for life. If you like it it is your choice.. Not everyone feels that way. Similarly you have no business telling people what drugs  they should or shouldnt take. Diablos opinion is as valid as yours I repeat you are not a psychiatrist. – Hide quoted text — Show quoted text –

Response:

Ward, If you want an _intelligent_ critical look at antidepressants, I recommend reading _Listening to Prozac_.  It should, at the very least, convince you that depression is very much a real medical (biological) condition that REQUIRES treatment, and it will also give you a good idea of the pros & cons of these drugs.  You just have to accept that you are biologically ill and need medice to treat your neurons.  You wouldn’t wonder if you should take medications if you had heart problems, etc.

Response:

Welp, I have made my decision and have chosen to try to combat my depression with a regimen of both therapy and medication. As a matter of fact, I write this only two hours after having taken my first dose of Effexor. So far, no bad effects, or for that matter, good effects noted. I guess for me, it makes the most sense to utilize every weapon in the arsenal to fight this life-sucking enemy. In no way, do I negate any thing that anyone who has responded to this thread may have intended. I believe that each of us ultimately finds the answer that is needed. I would like to thank all for their time and concern. Best wishes, Ward W

Response:

> Welp, I have made my decision and have chosen to try to combat my > depression with a regimen of both therapy and medication. As a matter of > fact, I write this only two hours after having taken my first dose of > Effexor. So far, no bad effects, or for that matter, good effects noted. > I guess for me, it makes the most sense to utilize every weapon in the > arsenal to fight this life-sucking enemy. In no way, do I negate any > thing that anyone who has responded to this thread may have intended. I > believe that each of us ultimately finds the answer that is needed. I > would like to thank all for their time and concern. > Best wishes, > Ward W

Best of luck Ward.. Of course it makes sense to use whatever is available and come out the other side.. lots and lots of people do… Theres no reason at all to think you wont be one Bob

Response:

>Be careful Diablo, that Effexor is VERY similar to the SSRIs and it might turn >you into a psycho/lunatic/killer/psychopath. I hope you have your guns locked >up when you take the Effexor Diablo. LOL Sheeesh man you are ridiculous.

I need to clean my guns.  They are already disassembled and I should lock the trigger mechanisms up before I start the Effexor.  Did you hear about yesterday’s school stabbings in Japan?  The perpetrator had been taking psychiatric medication. I wonder if he was on an SSRI. Diablo

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>Be careful Diablo, that Effexor is VERY similar to the SSRIs and it might turn >you into a psycho/lunatic/killer/psychopath. I hope you have your guns locked >up when you take the Effexor Diablo. LOL Sheeesh man you are ridiculous. > I need to clean my guns.  They are already disassembled and I should lock the > trigger mechanisms up before I start the Effexor.  Did you hear about yesterday’s > school stabbings in Japan?  The perpetrator had been taking psychiatric medication. > I wonder if he was on an SSRI.

A quantity of tranquillisers the Japanese press said… Bob – Hide quoted text — Show quoted text -> Diablo

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>LOL Diablo, you are whacked dude. Seriously Effexor is not much different than >SSRIs. Soon as you take that 75 mg Effexor tab, you are taking an extra strong >serotonin reuptake inhibitor. Thats all it is dude. As you go up in dosage you >get not only serotonin reuptake but also norephinephrine reuptake and at the >highest dosages even a little dopamine reuptake. GAD!!! Dopamine reuptake? That >means you are gonna be increasing dopamine Diablo. Yes, you better lock up >those guns dude, might go postal on us if you take that Effexor man. >Whoops, or it might be the other way around? Taking Effexor…or an >SSRI…might do the exact opposite. Making you a calmer, nicer, less irritable, >more focused human being. Wow, sounds like the profile for someone going postal >huh Diablo?

I know I’m whacked.  And I’m going to be taking 150mg of Effexor.  I’m not sure if I’m even depressed, I just feel so apathetic.  And I moved to a hick town, I’m in the ethnic minority (anglo), and wrecked my truck so I lost my job. No one wants to hire me because I don’t speak Spanish.  I am so bummed out and I am hoping that drugs will get me back on track. Diablo

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My husband takes it, for ADHD and anxiety. It has helped him immensely. If he has to keep taking it long-term, so be it….the benefits have far outweighed the drawbacks. It doesn’t work for everyone though.

– Hide quoted text — Show quoted text -> Nothing spooky about good old Effexor Ward. Effexor is a great antidepressant > and it will probably change your life for the better, possibly back to normal > and back to working full time. Its probably the strongest modern class > antidepressant and has relatively few side effects. Expect to feel dizzy and > sedated the first week, then possibly really activated for a while and "weird" > feeling. But after its been in your system a few weeks WATCH OUT cause the odds > are its gonna make you feel really really good. You are gonna love Effexor I > bet, once you get over your fear of antidepressants. > Modern antidepressants are all extremely safe Ward. Nothing to be scared of > man. > take care, > Eric > http://groups.yahoo.com/group/FactsAndFallaciesOfDepression > MIBS (Minimally Invasive Brain Stimulation) > http://www.musc.edu/psychiatry/fnrd/tms.htm > FIDO…Fuck It Drive On > Hey Eric, thanks much for the quick response. You know, part of the > problem, as I see it, is that I WILL like the stuff. Too much, in fact, > to want to get off of it. Also, your description about the first coupla > weeks of side effects reminds me too much of all the bad acid that I > used to gobble in my youth. May I ask you a personal question? Have you > been off anti-depressants for any significant time since you were first > prescribed them? If so, what has your experience been with "withdrawal" > and subsequent coping in drug free periods? Looking forward to hearing > from you again. > Best, > Ward W

Response:

hya yeah, i think we’ve all been there actually.  I have been on a few drugs over the years – stopped them also through my own "behavioural problems" and i never seemed to get any better. I am on 300mg of efexor (due to go up to 375mg a day) and 2 mg of flupenthixol.  Efexor has allowed me to get back to some kinda life; i am back at work and i am socialising again.  I also dont self-harm any more I still have very bad days where getting out of bed is a real effort, but on the whole I am beginning the long road of recovery.  I ahve stopped taking the efexor a few times, taken too many, etc, but that’s more to do with my state of mind rather than the meds. My advice to you would be to take the efexor and see how it goes.  you will probably experience some nausea or sickness in the first week, but it does get better – honestly! I wouldnt stop taking the efexor now as it has given me so much of my life back.. and I am willing to take the meds as long as it helps.  I reckon (as far as my shrink says anyway) that I will be on them long term.  I’ve been on my current meds combo now for about a year. Have you had any kinda diagnosis?  I have major depression with borderline personality disorder (although I dont believe I have the bpd – it’s just that I am female, self-harmed with an opinion of my own). Anyway, dont worry about taking the efexor.  try it out for yourself and see how it goes. good luck and keep us posted! lisa xxx

– Hide quoted text — Show quoted text -> Umm..here I sit with a months supply of this rather spooky > antidepressant in one hand and all my hopes and fears in another. Being > a good net junkie, I decided to check the NG’s to see if there was > anything being posted about this stuff. Boy, have I gotten an eyeful > from this group. > I’ve never been on any medication for depression before; however, I’ve > also never been in the situation that I’m currently in before. For just > about a year and a half, all that I have that energy to do is look at > internet porn and doze off for hours a day. Needless to say, the wife > and kiddies aren’t too pleased with this turn of events. I figure that > it has cost me about 90 grand in lost salary and just about everything > else in self esteem. I won’t go into particulars, but I brought all of > this on myself and now I have to dig out somehow. > There seems to be some good souls here, so I’ll just jump into the wind > and ask my naive question. Will this stuff do me any good? Do the > benefits outweigh the bugs or am I stepping onto a roller coaster that > may not stop when I want to get off? I would appreciate any sincere > comments. Thank You.                           Ward W

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Question:

anyone else had a nauseating response to sustained release effexor? i have only just had my first dose today, and about 4 hours after i took it i became nauseated to the point where nothing helps.  i just feel ILL! my usual antiD is a tricyclic but the doc decided this time she wanted me to try something different …dont worry i havent been switched, as it were…i had been holding it together OK for about 4 years :-/ anyone else had a similar response? — http://www.hamarana.com —

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<snip> >The nausea goes away if you keep taking the Effexor. Severe nausea is a common >side effect of both SSRIs and Effexor. My advice is to just keep on taking that >Effexor and expect some nausea and other side effects for the first couple >weeks til your body adjusts to it. Its a great antidepressant once it kicks in. >If you still have this nausea after a few weeks to a month then yeah >discontinue it. But the odds are the nausea is just an early adjustment side >effect. Its very common with that drug. >Eric >http://groups.yahoo.com/group/FactsAndFallaciesOfDepression >FIDO…Fuck It Drive On

thanks Eric.  I called my doc and she wondered if it was an interaction between the effexor and the antibiotics she started me on a couple of days ago (absolutely necessary, had a low grade infection for weeks and weeks).  so she told me to stop taking it until ive finished the antibiotics (8 days to go).  i can hang on til then.   but crikey, i never had anything like this with the tricyclics.  :(( — http://www.hamarana.com —

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– Hide quoted text — Show quoted text – ><snip> >The nausea goes away if you keep taking the Effexor. Severe nausea is a common >side effect of both SSRIs and Effexor. My advice is to just keep on taking that >Effexor and expect some nausea and other side effects for the first couple >weeks til your body adjusts to it. Its a great antidepressant once it kicks in. >If you still have this nausea after a few weeks to a month then yeah >discontinue it. But the odds are the nausea is just an early adjustment side >effect. Its very common with that drug. >Eric >http://groups.yahoo.com/group/FactsAndFallaciesOfDepression >FIDO…Fuck It Drive On >thanks Eric.  I called my doc and she wondered if it was an >interaction between the effexor and the antibiotics she started me on >a couple of days ago (absolutely necessary, had a low grade infection >for weeks and weeks).  so she told me to stop taking it until ive >finished the antibiotics (8 days to go).  i can hang on til then.   >but crikey, i never had anything like this with the tricyclics.  :(( >– >http://www.hamarana.com

there is a drug called maxalon ( metoclopramide) which is a fantastic anti-nausea drug.  if u take it each time u take the effexor it will greatly improve things.

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<snip> >there is a drug called maxalon ( metoclopramide) which is a fantastic >anti-nausea drug.  if u take it each time u take the effexor it will >greatly improve things.

good thinking, James, thanks. dunno why i didnt think of it myself. i’ll ask the doc to write me a script.  im on such a cocktail of meds at the moment i feel like a walking pharmacy. — http://www.hamarana.com —

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Or if you don’t want to go through that trouble, Peptol Bismol does a fine job at supressing nausea. Makes your poops black but hey that’s kind of cool anyway. – Hide quoted text — Show quoted text – > <snip> >there is a drug called maxalon ( metoclopramide) which is a fantastic >anti-nausea drug.  if u take it each time u take the effexor it will >greatly improve things. > good thinking, James, thanks. dunno why i didnt think of it myself. > i’ll ask the doc to write me a script.  im on such a cocktail of meds > at the moment i feel like a walking pharmacy. > — > http://www.hamarana.com > —

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Question:

Anybody tried sibutramine (Meridia, the so-called weight loss drug) as an antidepressant? How did it fare in comparison to other ADs (Effexor and Effexor XR in particular)? I heard some peculiar claims about it recently, is why I was asking. -elizabeth

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 > Meridia doesnt specifically increase neurotransmitters in the  > brain like ADs do. Rather they increase them everywhere  > in the body Not so, all ADs do whatever they do everywhere in the body.  For example, platelets (in blood) have a serotonin transporter, and all of the SSRIs block the reuptake of serotonin into platelets.  In fact, platelets are often used in the lab to measure things involving the serotonin transporter. Meridia

Question:

sang the following hymns: >Paxil doesnt usually cause aggression. It might make you agitated feeling in >the beginning while you are adjusting to it. Agitation is very common for all >SSRIs in the first several weeks. Aggression however is not. If Paxil makes you >aggressive or violent feeling thats not really normal. Its a sign that you >might be bipolar or a manic depressive. >Anytime you take an antidepressant and get a reaction like you described its a >possibility that what you are inducing is mania or hypomania. >Paxil makes me the opposite, makes me calmer and less irritable. All >antidepressants have that effect on me. >Eric

Thank you for your insights!

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- Hide quoted text — Show quoted text – > Hi everyone, > I found 2 people who seem to share my experience with seroxat. That is: > anger or agitation, about 15 to 1 hour after later. Feelings of violence. > Are there any more people who have this experience? My docs tell me it is > all me because it isn’t in the leaflet that comes with the AD. In USA you > are further on up the road regarding meds…so, please respond so I can use > your comments as evidence (anonymous; I will remove all aliases and email > adresses.) > Thanks in advance, yours truly > Vaipen

It might be. If you go and do a search on Medline, you will find most SSRI’s can increase not only feelings of major anxiety, but also hostile and aggressive feelings. I don’t have the citations on hand, but you can go do a Medline search. This isn’t to say the meds can’t be helpful..but their side effect profile is not proving much better then the old TCA antidepressants. Don’t let your doctor ignore your feelings. Just tell him you are not comfortable with them, and demand a sollution. As much as many SSRI’s have done good for me, I have found a few that really cause this nervous aggitation. Prozac is the most famous for this, but all other SSRI’s have found to be similar. I don’t want to scare you off from Paxil, but you have no reason to live in such a jittery, aggressive state. Demand your doctor try to fix the situation, or get another doctor. It’s a very horrible feeling…I know. Best of luck, Jay

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>Hi everyone, >I found 2 people who seem to share my experience with seroxat. That is: >anger or agitation, about 15 to 1 hour after later. Feelings of violence. >Are there any more people who have this experience? My docs tell me it is >all me because it isn’t in the leaflet that comes with the AD. In USA you >are further on up the road regarding meds…so, please respond so I can use >your comments as evidence (anonymous; I will remove all aliases and email >adresses.) >Thanks in advance, yours truly >Vaipen

Is seroxat an anti-depressent? If so, ad’s can cause mania in people who are prone to manic depression. Your doc should know this, it’s basic. For email replies remove the **** from my email address.

Response:

Hi everyone, I found 2 people who seem to share my experience with seroxat. That is: anger or agitation, about 15 to 1 hour after later. Feelings of violence. Are there any more people who have this experience? My docs tell me it is all me because it isn’t in the leaflet that comes with the AD. In USA you are further on up the road regarding meds…so, please respond so I can use your comments as evidence (anonymous; I will remove all aliases and email adresses.) Thanks in advance, yours truly Vaipen

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